Self-assembly of oriented antibody-decorated metal-organic framework nanocrystals for active-targeting applications

• Main Authors: Alt, Karen, Carraro, Francesco, Jap, Edwina, Linares-Moreau, Mercedes, Riccò, Raffaele, Righetto, Marcello, Bogar, Marco, Amenitsch, Heinz, Hashad, Rania A., Doonan, Christian, Hagemeyer, Christoph E., Falcaro, Paolo
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Physics; Antibodies; Crystallization
• Online Access: https://hdl.handle.net/10356/162713
• Institution: Nanyang Technological University

Antibody (Ab)-targeted nanoparticles are becoming increasingly important for precision medicine. By controlling the Ab orientation, targeting properties can be enhanced; however, to afford such an ordered configuration, cumbersome chemical functionalization protocols are usually required. This aspec...