Dual gate-controlled therapeutics for overcoming bacterium-induced drug resistance and potentiating cancer immunotherapy

• Main Authors: Zhang, Xiaodong, Chen, Xiaokai, Guo, Yuxin, Gao, Ge, Wang, Dongdong, Wu, Yinglong, Liu, Jiawei, Liang, Gaolin, Zhao, Yanli, Wu, Fu-Gen
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Chemistry; Bacterial Infection; Cancer Therapy
• 在線閱讀: https://hdl.handle.net/10356/162861

The presence of bacteria in the tumor can cause cancer resistance to chemotherapeutics. To fight against bacterium-induced drug resistance, herein we design self-traceable nanoreservoirs that are simultaneously loaded with gemcitabine (an anticancer drug) and ciprofloxacin (an antibiotic) and are de...