Insights into POT1 structural dynamics revealed by cryo-EM

Insights into POT1 structural dynamics revealed by cryo-EM

Telomeres are protein-DNA complexes that protect the ends of linear eukaryotic chromosomes. Mammalian telomeric DNA consists of 5'-(TTAGGG)n-3' double-stranded repeats, followed by up to several hundred bases of a 3' single-stranded G-rich overhang. The G-rich overhang is bound by the...

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Bibliographic Details
Main Authors: Smith, Emmanuel W., Lattmann, Simon, Liu, Barry Zhehui, Ahsan, Bilal, Rhodes, Daniela
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Biological sciences
Oligonucleotide
Binding Affinity
Online Access:https://hdl.handle.net/10356/163095
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Institution: Nanyang Technological University
Language: English

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https://hdl.handle.net/10356/163095

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