Label-free assessment of differentiation efficiency in iPSC-derived spinal cord progenitor cells via Magnetic Resonance Relaxometry (MRR)

• Main Authors: Tan, Jerome Zu Yao, Chen, Jiahui, Roxby, Daniel, Chooi, Wai Hon, Nguyen, Tan Dai, Ng, Shi-Yan, Chew, Sing Yian, Han, Jongyoon
• Other Authors: Interdisciplinary Graduate School (IGS)
• Format: Conference or Workshop Item
• Language: English
• Published: 2022
• Subjects: Science::Medicine::Tissue engineering; Engineering::Bioengineering; Cell Therapy; Critical Quality Attribute
• Online Access: https://hdl.handle.net/10356/163335; https://www.stemcell.org.sg/symposium22.html
• Institution: Nanyang Technological University

The advent of induced pluripotent stem cells (iPSC) has provided a promising solution to the replacement of damaged neurons, especially in spinal cord injuries. Despite its merits, differentiation of iPSCs is a highly variable process, prompting the need to reliably assess the degree of differentiat...