Characterization of the biosynthetic gene cluster and shunt products yields insights into the biosynthesis of balmoralmycin

• Main Authors: Ma, Guang-Lei, Xin, Lingyi, Liao, Yanghui, Chong, Zhi-Soon, Candra, Hartono, Pang, Li Mei, Lee, Sean Qiu En, Gakuubi, Martin Muthee, Ng, Siew Bee, Liang, Zhao-Xun
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Science::Biological sciences; Biosynthesis; Natural Product; Enzyme
• Online Access: https://hdl.handle.net/10356/163435
• Institution: Nanyang Technological University

Angucyclines are a family of structurally diverse, aromatic polyketides with some members that exhibit potent bioactivity. Angucyclines have also attracted considerable attention due to the intriguing biosynthetic origins that underlie their structural complexity and diversity. Balmoralmycin (com...