Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts
N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied....
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sg-ntu-dr.10356-1635002022-12-07T08:41:53Z Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts Wang, Hongling Chi, Robin Yonggui Huang, Xuan School of Physical and Mathematical Sciences Science::Chemistry Enantioselective Dual Catalysis N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied. The clear selection of cocatalysts has led to enhanced reactivity, increased yields, and/or improved stereoselectivity. This minireview is to provide readers with a brief overview of the development and applications of NHC and hydrogen-bond donor for dual catalytic reactions. We acknowledge financial support from the National Natural Science Foundation of China (No. 22001173), Basic and Applied Research Foundation of Guangdong (No. 2019A1515110906) and the Project of Department of Education of Guangdong Province (No. 2020KTSCX116), the Shenzhen Science and Technology Foundation (No. KQJSCX20180328100401788) and the Principal Foundation of SZU (No. 8570700000307). 2022-12-07T08:41:53Z 2022-12-07T08:41:53Z 2022 Journal Article Wang, H., Chi, R. Y. & Huang, X. (2022). Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts. European Journal of Organic Chemistry, 2022(27), e202200548-. https://dx.doi.org/10.1002/ejoc.202200548 1434-193X https://hdl.handle.net/10356/163500 10.1002/ejoc.202200548 2-s2.0-85134470132 27 2022 e202200548 en European Journal of Organic Chemistry © 2022 Wiley-VCH GmbH. All rights reserved. |
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Science::Chemistry Enantioselective Dual Catalysis Wang, Hongling Chi, Robin Yonggui Huang, Xuan Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
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N-heterocyclic carbene (NHC) catalysis has become a versatile catalysis strategy for building molecules via unique reaction modes. Dual catalytic processes using NHCs in combination with additional modulating agents such as another organocatalyst or transition-metal catalyst have also been studied. The clear selection of cocatalysts has led to enhanced reactivity, increased yields, and/or improved stereoselectivity. This minireview is to provide readers with a brief overview of the development and applications of NHC and hydrogen-bond donor for dual catalytic reactions. |
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School of Physical and Mathematical Sciences |
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School of Physical and Mathematical Sciences Wang, Hongling Chi, Robin Yonggui Huang, Xuan |
format |
Article |
author |
Wang, Hongling Chi, Robin Yonggui Huang, Xuan |
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Wang, Hongling |
title |
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
title_short |
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
title_full |
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
title_fullStr |
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
title_full_unstemmed |
Enantioselective dual catalysis of N-heterocyclic carbene and hydrogen-bond donor organocatalysts |
title_sort |
enantioselective dual catalysis of n-heterocyclic carbene and hydrogen-bond donor organocatalysts |
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2022 |
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https://hdl.handle.net/10356/163500 |
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1753801153606320128 |