Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact
Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing.
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sg-ntu-dr.10356-1636802023-03-05T16:51:44Z Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact Zhao, Liuyang Shi, Yu Lau, Harry Cheuk-Hay Liu, Weixin Luo, Guangwen Wang, Guoping Liu, Changan Pan, Yasi Zhou, Qiming Ding, Yanqiang Sung, Joseph Jao Yiu Yu, Jun Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Gut Virome Ultra-Deep Metagenomic Sequencing Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing. Published version This study was supported by National Key R&D Program of China (2020YFA0509200/2020YFA0509203), Research Grants Council Research Impact Fund Hong Kong (R4632-21F), Research Grants Council Theme-Based Research Scheme Hong Kong (T21-705/20-N), Research Grants Council Collaborative Research Fund (C4039-19GF, C7065-18GF), Research Grants Council General Research Fund Hong Kong (14163817), Vice-Chancellor’s Discretionary Fund Chinese University of Hong Kong. 2022-12-13T08:59:58Z 2022-12-13T08:59:58Z 2022 Journal Article Zhao, L., Shi, Y., Lau, H. C., Liu, W., Luo, G., Wang, G., Liu, C., Pan, Y., Zhou, Q., Ding, Y., Sung, J. J. Y. & Yu, J. (2022). Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact. Gastroenterology, 163(3), 699-711. https://dx.doi.org/10.1053/j.gastro.2022.05.048 0016-5085 https://hdl.handle.net/10356/163680 10.1053/j.gastro.2022.05.048 35679948 2-s2.0-85134482936 3 163 699 711 en Gastroenterology © 2022 The Author(s). Published by Elsevier Inc. on behalf of the AGA Institute. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf |
| institution |
Nanyang Technological University |
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NTU Library |
| continent |
Asia |
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Singapore Singapore |
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English |
| topic |
Science::Medicine Gut Virome Ultra-Deep Metagenomic Sequencing |
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Science::Medicine Gut Virome Ultra-Deep Metagenomic Sequencing Zhao, Liuyang Shi, Yu Lau, Harry Cheuk-Hay Liu, Weixin Luo, Guangwen Wang, Guoping Liu, Changan Pan, Yasi Zhou, Qiming Ding, Yanqiang Sung, Joseph Jao Yiu Yu, Jun Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| description |
Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing. |
| author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Zhao, Liuyang Shi, Yu Lau, Harry Cheuk-Hay Liu, Weixin Luo, Guangwen Wang, Guoping Liu, Changan Pan, Yasi Zhou, Qiming Ding, Yanqiang Sung, Joseph Jao Yiu Yu, Jun |
| format |
Article |
| author |
Zhao, Liuyang Shi, Yu Lau, Harry Cheuk-Hay Liu, Weixin Luo, Guangwen Wang, Guoping Liu, Changan Pan, Yasi Zhou, Qiming Ding, Yanqiang Sung, Joseph Jao Yiu Yu, Jun |
| author_sort |
Zhao, Liuyang |
| title |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| title_short |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| title_full |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| title_fullStr |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| title_full_unstemmed |
Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact |
| title_sort |
uncovering 1058 novel human enteric dna viruses through deep long-read third-generation sequencing and their clinical impact |
| publishDate |
2022 |
| url |
https://hdl.handle.net/10356/163680 |
| _version_ |
1759856474679410688 |