Uncovering 1058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact

• Main Authors: Zhao, Liuyang, Shi, Yu, Lau, Harry Cheuk-Hay, Liu, Weixin, Luo, Guangwen, Wang, Guoping, Liu, Changan, Pan, Yasi, Zhou, Qiming, Ding, Yanqiang, Sung, Joseph Jao Yiu, Yu, Jun
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Gut Virome; Ultra-Deep Metagenomic Sequencing
• Online Access: https://hdl.handle.net/10356/163680
• Institution: Nanyang Technological University

Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing.