Phenotypic and integrated analysis of a comprehensive Pseudomonas aeruginosa PAO1 library of mutants lacking cyclic-di-GMP-related genes

• Main Authors: Eilers, Kira, Yam, Joey Kuok Hoong, Morton, Richard, Yong, Adeline Mei Hui, Brizuela, Jaime, Hadjicharalambous, Corina, Liu, Xianghui, Givskov, Michael, Rice, Scott A., Filloux, Alain
• Other Authors: Singapore Centre for Environmental Life Sciences and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Pseudomonas; Biofilm
• Online Access: https://hdl.handle.net/10356/163820
• Institution: Nanyang Technological University

Pseudomonas aeruginosa is a Gram-negative bacterium that is able to survive and adapt in a multitude of niches as well as thrive within many different hosts. This versatility lies within its large genome of ca. 6 Mbp and a tight control in the expression of thousands of genes. Among the regulatory m...