Liquid-liquid phase separation of telomeric nucleosome array is mediated by TRF2

• Main Author: Neo, Qi Ying
• Other Authors: Lars Nordenskiöld
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/163839
• Institution: Nanyang Technological University

Telomeres, the ends of the chromosomes, have always been an interesting area of structural genomic research as they are known to play crucial roles in ageing and cancer. The organization of human telomeric chromatin has been implicated in its functional roles as telomeres are the protectors of the e...