Asymmetric conjugate addition to enones catalyzed by novel bisisoquinoline/transition metal complexes

• Main Author: Tee, Chin Yaw.
• Other Authors: Zaher Judeh
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Chemicals and manufacture
• Online Access: http://hdl.handle.net/10356/16424
• Institution: Nanyang Technological University

Novel bisisoquinoline-based ligands have been synthesized and used in various asymmetric reactions by Mr. Gao Qi in our lab. Good yields of up to 92% and moderate ee of up to 35% were obtained for the enantioselective conjugate addition of Grignard reagents to cyclohexenones to obtain the desired 1,...