Dissecting the role of diabetes-associated PAX4 polymorphisms in modulating pancreatic beta cell development and function
Diabetes is a major chronic disease with an excessive healthcare burden on society. A missense variant within the coding region of the PAX4 gene (rs2233580, R192H) is associated with T2D in East Asians. In mice, Pax4 is essential for beta cell formation but neither the role of diabetes associate...
Saved in:
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Thesis-Doctor of Philosophy |
| 語言: | English |
| 出版: |
Nanyang Technological University
2023
|
| 主題: | |
| 在線閱讀: | https://hdl.handle.net/10356/164374 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
| 機構: | Nanyang Technological University |
| 語言: | English |