Dimethyl fumarate reduces inflammation in chronic active multiple sclerosis lesions

• Main Authors: Zinger, Nicole, Ponath, Gerald, Sweeney, Elizabeth, Nguyen, Thanh D., Lo, Chih Hung, Diaz, Ivan, Dimov, Alexey, Teng, Leilei, Zexter, Lily, Comunale, Joseph, Wang, Yi, Pitt, David, Gauthier, Susan A.
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Science::Medicine; Dimethyl Fumarate; Multiple Sclerosis
• 在線閱讀: https://hdl.handle.net/10356/164429
• 機構: Nanyang Technological University

BACKGROUND AND OBJECTIVES: To determine the effects of dimethyl fumarate (DMF) and glatiramer acetate on iron content in chronic active lesions in patients with multiple sclerosis (MS) and in human microglia in vitro. METHODS: This was a retrospective observational study of 34 patients with relapsin...