Advanced strategies to enhance the performances of crystallization and precipitation of biopharmaceuticals

• المؤلف الرئيسي: Pu, Siyu
• مؤلفون آخرون: Kunn Hadinoto Ong
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Engineering::Chemical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164549

This dissertation describes advanced crystallization and precipitation strategies to improve process efficiency and product quality of biopharmaceuticals using bioactive glycopeptide vancomycin hydrochloride (Van) and protein lysozyme (LYZ) as the model biopharmaceuticals. The first study focuses on...