Dendritic cell-intrinsic Ezh2 expression maintains thymic homeostasis and prevents premature thymic involution
Ezh2, a well-known histone methyltransferase, was previously shown to regulate the integrin-dependent migration of dendritic cells (DCs) via the non-canonical cytosolic methylation of the cytoskeleton protein Talin. It remained unclear if Ezh2 has other functional roles in DCs. Here, we found that D...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2023
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Online Access: | https://hdl.handle.net/10356/164947 |
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Institution: | Nanyang Technological University |
Language: | English |