Dendritic cell-intrinsic Ezh2 expression maintains thymic homeostasis and prevents premature thymic involution

• المؤلف الرئيسي: Sint Thida Bo
• مؤلفون آخرون: Su I-Hsin
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2023
• الموضوعات: Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/164947

Ezh2, a well-known histone methyltransferase, was previously shown to regulate the integrin-dependent migration of dendritic cells (DCs) via the non-canonical cytosolic methylation of the cytoskeleton protein Talin. It remained unclear if Ezh2 has other functional roles in DCs. Here, we found that D...