Dendritic cell-intrinsic Ezh2 expression maintains thymic homeostasis and prevents premature thymic involution

• 主要作者: Sint Thida Bo
• 其他作者: Su I-Hsin
• 格式: Thesis-Doctor of Philosophy
• 語言: English
• 出版: Nanyang Technological University 2023
• 主題: Science::Biological sciences
• 在線閱讀: https://hdl.handle.net/10356/164947

Ezh2, a well-known histone methyltransferase, was previously shown to regulate the integrin-dependent migration of dendritic cells (DCs) via the non-canonical cytosolic methylation of the cytoskeleton protein Talin. It remained unclear if Ezh2 has other functional roles in DCs. Here, we found that D...