Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides

• Main Authors: Guo, Qi, Zou, Guijin, Qian, Xuliang, Chen, Shujun, Gao, Huajian, Yu, Jing
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Hydrogen Bonding; Peptides
• Online Access: https://hdl.handle.net/10356/165247
• Institution: Nanyang Technological University

Marine mussels achieve strong underwater adhesion by depositing mussel foot proteins (Mfps) that form coacervates during the protein secretion. However, the molecular mechanisms that govern the phase separation behaviors of the Mfps are still not fully understood. Here, we report that GK-16*, a pept...