Differential expression of Connexin 43 during dental pulp inflammation and its role in pulpal healing: a translational study determining effect of Connexin 43 downregulation in treatment of pulpitis

• Main Author: Lim, Wen Yi
• Other Authors: David Lawrence Becker
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Biological sciences::Human anatomy and physiology
• Online Access: https://hdl.handle.net/10356/165279
• Institution: Nanyang Technological University

Dental pulp inflammation, or pulpitis, is a common painful dental condition. Connexin 43 (Cx43) is a building block for cellular portals of communication such as hemichannels and gap junctions. These play key roles in coordinating an immune response during pulpitis. It is hypothesized that pathologi...