Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy

• Main Authors: Ding, Chendi, Chen, Chunbo, Zeng, Xiaowei, Chen, Hongzhong, Zhao, Yanli
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Biomedical Nanotechnology; Cancer Therapy
• Online Access: https://hdl.handle.net/10356/165552
• Institution: Nanyang Technological University

Prodrugs are chemically modified drug molecules that are inactive before administration. After administration, they are converted in situ to parent drugs and induce the mechanism of action. The development of prodrugs has upgraded conventional drug treatments in terms of bioavailability, targeting,...