Construction of recombinant adenovirus encoding both TGF-beta 3 and ShRNA targeting type I collagen gene.
The tissue engineering of Mesenchymal stem cells (MSC) are promising in treatment of cartilage defects and the repairmen of damaged cartilage. But the highly expression of type I collagen in the cells, which will result in fibrocartilage, is still a big problem to be overcome. Basing on RNA interfer...
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Format: | Final Year Project |
Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/10356/16558 |
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Institution: | Nanyang Technological University |
Language: | English |