Construction of recombinant adenovirus encoding both TGF-beta 3 and ShRNA targeting type I collagen gene.

• المؤلف الرئيسي: Liu, Chengzheng.
• مؤلفون آخرون: Wang Dongan
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2009
• الموضوعات: DRNTU::Engineering::Chemical engineering::Biotechnology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/16558

The tissue engineering of Mesenchymal stem cells (MSC) are promising in treatment of cartilage defects and the repairmen of damaged cartilage. But the highly expression of type I collagen in the cells, which will result in fibrocartilage, is still a big problem to be overcome. Basing on RNA interfer...