Development and evaluation of chemical modifications and conjugations for nucleic acid therapeutic delivery

Antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) are synthetic nucleic acid molecules that could bind complementarily to the specific RNA targets directly or with the aid of specific protein complex before expressing their potent gene silencing effects in different mechanisms of...

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Bibliographic Details
Main Author: Nguyen, Minh Duc
Other Authors: Phan Anh Tuan
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2023
Subjects:
Online Access:https://hdl.handle.net/10356/165623
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Institution: Nanyang Technological University
Language: English