Development and evaluation of chemical modifications and conjugations for nucleic acid therapeutic delivery
Antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) are synthetic nucleic acid molecules that could bind complementarily to the specific RNA targets directly or with the aid of specific protein complex before expressing their potent gene silencing effects in different mechanisms of...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/165623 |
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| Institution: | Nanyang Technological University |
| Language: | English |