Stability of peptide nucleic acid influenced by peptoid-like sidechains : MD simulation study.
Peptide nucleic acid (PNA) is one of the most promising candidates for next-generation antisense technology. Other than high specificity and ability to be engineered to target, it offers enhanced stability, fidelity and strand invasion capabilities. Rapid developments in this field include synthesis...
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Format: | Final Year Project |
Language: | English |
Published: |
2010
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Online Access: | http://hdl.handle.net/10356/38930 |
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Institution: | Nanyang Technological University |
Language: | English |