Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids

RNA triplex structures play vital roles in regulating various biological processes, and have attracted a Jot of interest in designing TFOs (triplex-fonning oligomers) that could selectively and specifically bind to the nuclei acid duplex. The PNAs (peptide nucleic acids), with the natural nucleic ac...

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Bibliographic Details
Main Author: Yuan, Zhen
Other Authors: Chen Gang
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/69812
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Institution: Nanyang Technological University
Language: English