Recognition of A-U and U-A base pairs in RNA duplexes by modified peptide nucleic acids

• Main Author: Yuan, Zhen
• Other Authors: Chen Gang
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/69812
• Institution: Nanyang Technological University

RNA triplex structures play vital roles in regulating various biological processes, and have attracted a Jot of interest in designing TFOs (triplex-fonning oligomers) that could selectively and specifically bind to the nuclei acid duplex. The PNAs (peptide nucleic acids), with the natural nucleic ac...