A C-terminal peptide of TFPI-1 facilitates cytosolic delivery of nucleic acid cargo into mammalian cells

A C-terminal peptide of TFPI-1 facilitates cytosolic delivery of nucleic acid cargo into mammalian cells

Efficient intracellular nucleic acid delivery into mammalian cells remains a long-standing challenge owing to poor cell permeability and uptake of naked nucleic acids across the cell membrane and limited cargo stability. Conventional delivery methods have several drawbacks, such as cytotoxicity, lim...

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Bibliographic Details
Main Authors: Fazil, Mobashar Hussain Urf Turabe, Chalasani, Madhavi Latha Somaraju, Choong, Yeu Khai, Schmidtchen, Artur, Verma, Navin Kumar, Saravanan, Rathi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Science::Medicine
Host Defence Peptide
Intracellular Gene Delivery
Online Access:https://hdl.handle.net/10356/151502
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/151502

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