Developing a hollow fiber infection model system to determine the PK/PD of conjugated oligoelectrolytes against clinically relevant pathogens

• Main Author: Wang, Ruolan
• Other Authors: Staffan Kjelleberg
• Format: Thesis-Master by Research
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/165631
• Institution: Nanyang Technological University

The ability of microbes to develop antimicrobial resistance gives rise to the emergence of drug resistant strains whose infections are difficult to treat. Therefore, there is a pressing need for the development of novel drugs. One of the key stages in the drug discovery pipeline is understanding...