An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus

• Main Authors: Zhang, Kaixi, Limwongyut, Jakkarin, Moreland, Alex S., Wei, Samuel Chan Jun, Jim, Tania Jia Min, Sun, Yan, Shin, Sung Jae, Kim, Su-Young, Jhun, Byung Woo, Pethe, Kevin, Bazan, Guillermo C.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Mycobacterium abscessus; Conjugated oligoelectrolyte
• Online Access: https://hdl.handle.net/10356/174790; https://www.science.org/doi/10.1126/scitranslmed.adi7558
• Institution: Nanyang Technological University

Infections caused by nontuberculous mycobacteria have increased more than 50% in the past two decades and more than doubled in the elderly population. Mycobacterium abscessus (Mab), one of the most prevalent of these rapidly growing species, is intrinsically resistant to numerous antibiotics. Curren...