Adiposity impacts cognitive function in Asian populations: an epidemiological and Mendelian Randomization study

• Main Authors: Mina, Theresia, Yew, Yik Weng, Ng, Hong Kiat, Sadhu, Nilanjana, Wansaicheong, Gervais, Dalan, Rinkoo, Low, Dorrain Yan Wen, Lam, Benjamin Chih Chiang, Riboli, Elio, Lee, Eng Sing, Ngeow, Joanne, Elliott, Paul, Griva, Konstadina, Loh, Marie, Lee, Jimmy, Chambers, John
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Adiposity; Visceral Adiposity
• Online Access: https://hdl.handle.net/10356/165808
• Institution: Nanyang Technological University

Background: Obesity and related metabolic disturbances including diabetes, hypertension and hyperlipidemia predict future cognitive decline. Asia has a high prevalence of both obesity and metabolic disease, potentially amplifying the future burden of dementia in the region. We aimed to investigate t...