Identification of biomarker in patients on low dose warfarin : an iTRAQ-coupled LC-MS/MS approach

• Main Author: Koh, Regina Hwee Chen.
• Other Authors: Chen Wei Ning, William
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Engineering::Chemical engineering::Biotechnology
• Online Access: http://hdl.handle.net/10356/16589
• Institution: Nanyang Technological University

Warfarin is one of the most widely used oral anticoagulant. However, the dosage of warfarin given to patients is very critical as an overdose may lead to severe bleeding or an under-dosing may lead to clotting of the blood. Hence, it is important to find clues and leads to enable medical professiona...