Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo

• Main Authors: Chew, Marvin, Ye, Weijian, Omelianczyk, Radoslaw Igor, Pasaje, Charisse Flerida, Hoo, Regina, Chen, Qingfeng, Niles, Jacquin C., Chen, Jianzhu, Preiser, Peter
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Membrane Antigen; Genomic DNA
• Online Access: https://hdl.handle.net/10356/168657
• Institution: Nanyang Technological University

Plasmodium falciparum has developed extensive mechanisms to evade host immune clearance. Currently, most of our understanding is based on in vitro studies of individual parasite variant surface antigens and how this relates to the processes in vivo is not well-understood. Here, we have used a humani...