Analysis of helicobacter pylori antimicrobial susceptibility and virulence genes.

• Main Author: Goh, Hui Lin.
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/16898
• Institution: Nanyang Technological University

Helicobacter pylori, which causes gastric ulcers and cancers, contains the polymorphic virulence genes cagA and vacA. Differences in the cagA EPIYA motifs and polymorphisms of vacA signal (s), middle (m) and intermediate (i) regions were thought to be important in determining disease severity. This...