Analogy or fallacy, unsafe chemical alternatives: mechanistic insights into energy metabolism dysfunction induced by Bisphenol analogs in HepG2 cells

• Main Authors: Jia, Shenglan, Marques Dos Santos, Mauricius, Li, Caixia, Fang, Mingliang, Sureshkumar, Mithusha, Snyder, Shane Allen
• Other Authors: Nanyang Environment and Water Research Institute
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Environmental engineering; Bisphenol Analogues; Global Metabolomics
• Online Access: https://hdl.handle.net/10356/169267
• Institution: Nanyang Technological University

Bisphenol analogs (BPs) are widely used as industrial alternatives for Bisphenol A (BPA). Their toxicity assessment in humans has mainly focused on estrogenic activity, while other toxicity effects and mechanisms resulting from BPs exposure remain unclear. In this study, we investigated the effects...