Alkynone β-trifluoroborates: a new class of amine-specific biocompatible click reagents

• Main Authors: Teng, Shenghan, Ng, Elvis Wang Hei, Zhang, Zhenguo, Soon, Chee Ning, Xu, Hailun, Li, Ruifang, Hirao, Hajime, Loh, Teck-Peng
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Alkynones; Alkynyls
• Online Access: https://hdl.handle.net/10356/169291
• Institution: Nanyang Technological University

Amine-targeting reactions that work under biocompatible conditions or in water are green processes that are extremely useful for the synthesis of functional materials and biotherapeutics. Unfortunately, despite the usefulness of this reaction, there are very few good amine-specific click methods rep...