Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress

• Main Authors: Li, Jialin, Qu, Wan, Hu, Chengcheng, Liu, Zongbao, Yan, He
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Chemistry; Gut Viruses; Depression
• Online Access: https://hdl.handle.net/10356/169565
• Institution: Nanyang Technological University

In clinical practice, antidepressant drugs are widely used to treat depression. Previous studies have attention to the impact of antidepressants on the bacterial microbiome, while the role of these drugs in the gut virome is still unclear.