Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress

In clinical practice, antidepressant drugs are widely used to treat depression. Previous studies have attention to the impact of antidepressants on the bacterial microbiome, while the role of these drugs in the gut virome is still unclear.

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Main Authors:	Li, Jialin, Qu, Wan, Hu, Chengcheng, Liu, Zongbao, Yan, He
Other Authors:	School of Chemistry, Chemical Engineering and Biotechnology
Format:	Article
Language:	English
Published:	2023
Subjects:	Science::Chemistry Gut Viruses Depression
Online Access:	https://hdl.handle.net/10356/169565
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-1695652023-07-28T15:31:46Z Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress Li, Jialin Qu, Wan Hu, Chengcheng Liu, Zongbao Yan, He School of Chemistry, Chemical Engineering and Biotechnology NTU Food Technology Centre Science::Chemistry Gut Viruses Depression In clinical practice, antidepressant drugs are widely used to treat depression. Previous studies have attention to the impact of antidepressants on the bacterial microbiome, while the role of these drugs in the gut virome is still unclear. Published version This work was supported by the National Natural Science Foundation of China (grant no. 32170064). 2023-07-24T08:18:06Z 2023-07-24T08:18:06Z 2023 Journal Article Li, J., Qu, W., Hu, C., Liu, Z. & Yan, H. (2023). Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress. Frontiers in Microbiology, 14, 1132403-. https://dx.doi.org/10.3389/fmicb.2023.1132403 1664-302X https://hdl.handle.net/10356/169565 10.3389/fmicb.2023.1132403 37125190 2-s2.0-85159800994 14 1132403 en Frontiers in Microbiology © 2023 Li, Qu, Hu, Liu and Yan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Chemistry Gut Viruses Depression
spellingShingle	Science::Chemistry Gut Viruses Depression Li, Jialin Qu, Wan Hu, Chengcheng Liu, Zongbao Yan, He Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
description	In clinical practice, antidepressant drugs are widely used to treat depression. Previous studies have attention to the impact of antidepressants on the bacterial microbiome, while the role of these drugs in the gut virome is still unclear.
author2	School of Chemistry, Chemical Engineering and Biotechnology
author_facet	School of Chemistry, Chemical Engineering and Biotechnology Li, Jialin Qu, Wan Hu, Chengcheng Liu, Zongbao Yan, He
format	Article
author	Li, Jialin Qu, Wan Hu, Chengcheng Liu, Zongbao Yan, He
author_sort	Li, Jialin
title	Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
title_short	Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
title_full	Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
title_fullStr	Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
title_full_unstemmed	Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress
title_sort	antidepressants amitriptyline, fluoxetine, and traditional chinese medicine xiaoyaosan caused alterations in gut dna virome composition and function in rats exposed chronic unpredictable mild stress
publishDate	2023
url	https://hdl.handle.net/10356/169565
_version_	1773551305795567616

Antidepressants amitriptyline, fluoxetine, and traditional Chinese medicine Xiaoyaosan caused alterations in gut DNA virome composition and function in rats exposed chronic unpredictable mild stress

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