Conditioning on parental mating types can reduce necessary assumptions for Mendelian randomization

Mendelian randomization (MR) has become a common tool used in epidemiological studies. However, when confounding variables are correlated with the instrumental variable (in this case, a genetic/variant/marker), the estimation can remain biased even with MR. We propose conditioning on parental mating...

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Bibliographic Details
Main Authors: Ejima, Keisuke, Liu, Nianjun, Mestre, Luis Miguel, de Los Campos, Gustavo, Allison, David B.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/169677
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Institution: Nanyang Technological University
Language: English