Selective binding of retrotransposons by ZFP352 facilitates the timely dissolution of totipotency network

• Main Authors: Li, Zhengyi, Xu, Haiyan, Li, Jiaqun, Xu, Xiao, Wang, Junjiao, Wu, Danya, Zhang, Jiateng, Liu, Juan, Xue, Ziwei, Zhan, Guankai, Tan, Bobby Cheng Peow, Chen, Di, Chan, Yun-Shen, Ng, Huck Hui, Liu, Wanlu, Hsu, Chih-Hung, Zhang, Dan, Shen, Yang, Liang, Hongqing
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Embryo Development; Gene Expression Regulation
• Online Access: https://hdl.handle.net/10356/169767
• Institution: Nanyang Technological University

Acquisition of new stem cell fates relies on the dissolution of the prior regulatory network sustaining the existing cell fates. Currently, extensive insights have been revealed for the totipotency regulatory network around the zygotic genome activation (ZGA) period. However, how the dissolution of...