Vascular smooth muscle cells in low SYNTAX scores coronary artery disease exhibit proinflammatory transcripts and proteins correlated with IL1B activation

• Main Authors: Dorajoo, Rajkumar, Ihsan, Mario Octavianus, Liu, Wenting, Lim, Hwee Ying, Angeli, Veronique, Park, Sung-Jin, Chan, Joyce M. S., Lin, Xiao Yun, Ong, Mei Shan, Muniasamy, Umamaheswari, Lee, Chi-Hang, Gurung, Rijan, Ho, Hee Hwa, Foo, Roger, Liu, Jianjun, Kofidis, Theo, Lee, Chuen Neng, Sorokin, Vitaly A.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; SYNTAX Score; Vascular Smooth Muscle Cells
• Online Access: https://hdl.handle.net/10356/170886
• Institution: Nanyang Technological University

Background and aims: The SYNTAX score is clinically validated to stratify number of lesions and pattern of CAD. A better understanding of the underlying molecular mechanisms influencing the pattern and complexity of coronary arteries lesions among CAD patients is needed. Methods: Human arterial biop...