Dual strategy for ¹³C-Metabolic flux analysis of central carbon and energy metabolism in mammalian cells based on LC-isoMRM-MS

• المؤلفون الرئيسيون: Zheng, Jie, Yang, Junjie, Liang, Xu, Fang, Mingliang, Wang, Yulan
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Science::Medicine; Science::Biological sciences; Central Carbon and Energy Metabolism; Carboxyl and Phosphate Metabolites
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/171182

Central carbon and energy metabolism are the most concerned metabolic pathways in 13C-Metabolic flux analysis (13C-MFA). However, some α-keto acids, ribonucleoside triphosphate (NTPs) and deoxyribonucleoside triphosphate (dNTPs) involved in central carbon and energy metabolism pathways were unstable...