Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae

• Main Authors: Goh, Corinna Jie Hui, Cui, Liang, Wong, Jin Huei, Lewis, Jacqueline, Goh, Megan, Kong, Kiat Whye, Yang, Lay Kien, Alfatah, Mohammad, Kanagasundaram, Yoganathan, Hoon, Shawn, Arumugam, Prakash
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Phthalic Acids; Saccharomyces cerevisiae Proteins
• Online Access: https://hdl.handle.net/10356/171293
• Institution: Nanyang Technological University

Phthalates are ubiquitously used as plasticizers in various consumer care products. Diethyl phthalate (DEP), one of the main phthalates, elicits developmental and reproductive toxicities but the underlying mechanisms are not fully understood. Chemogenomic profiling of DEP in S. cerevisiae revealed t...