Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment

by Wong, Alex, Chen, Sixun, Yang, Lay Kien, Kanagasundaram, Yoganathan, Crasta, Karen
Published 2023

Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment

by Wong, Alex, Chen, Sixun, Yang, Lay Kien, Kanagasundaram, Yoganathan, Crasta, Karen Carmelina
Published 2020

Diversity and biosynthetic potential of fungi isolated from St. John's Island, Singapore

by Munusamy, Madhaiyan, Tan, Kenneth, Nge, Choy Eng, Gakuubi, Martin Muthee, Crasta, Sharon, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published 2023

Enhancing the discovery of bioactive secondary metabolites from fungal endophytes using chemical elicitation and variation of fermentation media

by Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published 2022

Transcriptomic and metabolomic characterization of antibacterial activity of Melastoma dodecandrum

by Poh, Wee Han, Nur Syahirah Ruhazat, Yang, Lay Kien, Shivhare, Devendra, Lim, Peng Ken, Kanagasundaram, Yoganathan, Rice, Scott A., Mutwil, Marek
Published 2024

CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932

by Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Lim, Chun Teck, Ma, Guang-Lei, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published 2023

Chemical elicitation as an avenue for discovery of bioactive compounds from fungal endophytes

by Munusamy, Madhaiyan, Ching, Kuan Chieh, Yang, Lay Kien, Crasta, Sharon, Gakuubi, Martin Muthee, Chee, Zhao Yan, Wibowo, Mario, Leong, Chung Yan, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published 2023

Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae

by Goh, Corinna Jie Hui, Cui, Liang, Wong, Jin Huei, Lewis, Jacqueline, Goh, Megan, Kong, Kiat Whye, Yang, Lay Kien, Alfatah, Mohammad, Kanagasundaram, Yoganathan, Hoon, Shawn, Arumugam, Prakash
Published 2023

Identification of a biosynthetic gene cluster for the polyene macrolactam sceliphrolactam in a Streptomyces strain isolated from mangrove sediment

by Hoang, Kim Le Mai, Tran, Hoa Thi, Low, Zhen Jie, Pang, Li Mei, Ding, Yichen, Cheang, Qing Wei, Li, Jinming, Liu, Xue-Wei, Kanagasundaram, Yoganathan, Yang, Liang, Liang, Zhao-Xun
Published 2018

Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723

by Sinha, Swati, Nge, Choy-Eng, Leong, Chung Yan, Ng, Veronica, Crasta, Sharon, Goh, Falicia, Low, Kia-Ngee, Zhang, Huibin, Arumugam, Prakash, Lezhava, Alexander, Chen, Swaine L., Kanagasundaram, Yoganathan, Ng, Siew Bee, Eisenhaber, Frank, Eisenhaber, Birgit, Mohammad Alfatah
Published 2019

Identification and engineering of 32 membered antifungal macrolactone notonesomycins

by Goh, Falicia, Zhang, Mingzi M., Lim, Tian Ru, Low, Kia Ngee, Nge, Choy Eng, Heng, Elena, Yeo, Wan Lin, Sirota, Fernanda L., Crasta, Sharon, Tan, Zann, Ng, Veronica, Leong, Chung Yan, Zhang, Huibin, Lezhava, Alexander, Chen, Swaine L., Hoon, Shawn S., Eisenhaber, Frank, Eisenhaber, Birgit, Kanagasundaram, Yoganathan, Wong, Fong T., Ng, Siew Bee
Published 2021

Genomic, transcriptomic, and metabolomic analysis of Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites

by Julca, Irene, Mutwil-Anderwald, Daniela, Manoj, Vaishnervi, Khan, Zahra, Lai, Soak Kuan, Yang, Lay K., Beh, Ing Tsyr, Dziekan, Jerzy, Lim, Yoon P., Lim, Shen Kiat, Low, Yee W., Lam, Yuen In, Tjia, Seth, Mu, Yuguang, Tan, Qiao Wen, Nuc, Przemyslaw, Choo, Le M., Khew, Gillian, Shining, Loo, Kam, Antony, Tam, James P., Bozdech, Zbynek, Schmidt, Maximilian, Usadel, Bjoern, Kanagasundaram, Yoganathan, Alseekh, Saleh, Fernie, Alisdair, Li, Hoi Y., Mutwil, Marek
Published 2023