Evaluating spray gelation and spray freeze drying as the granulation method to prepare oral tablets of amorphous drug nanoplex

• Main Authors: Chua, Angeline, Ng, He Tong, Cheow, Wean Sin, Hadinoto, Kunn
• 其他作者: School of Chemistry, Chemical Engineering and Biotechnology
• 格式: Article
• 語言: English
• 出版: 2023
• 主題: Engineering::Bioengineering; Drug Nanoparticles; Amorphous Drugs
• 在線閱讀: https://hdl.handle.net/10356/171395
• 機構: Nanyang Technological University

Amorphous drug nanoplex represents one of the most promising solubility enhancement strategies of poorly-soluble drugs. Solubility enhancement capability of nanoplex hitherto has been demonstrated for nanoplex suspension and lyophilized/spray-dried nanoplex, but not for its oral tablets. Using cipro...