Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells

Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells

Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loa...

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Main Authors: Onbasli, Kubra, Demirci, Gozde, Isik, Furkan, Durmusoglu, Emek Goksu, Demir, Hilmi Volkan, Acar, Havva Yagci
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Science::Chemistry
Nanoplatelet
Cancer Cells
Online Access:https://hdl.handle.net/10356/172114
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1721142023-11-24T02:17:18Z Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells Onbasli, Kubra Demirci, Gozde Isik, Furkan Durmusoglu, Emek Goksu Demir, Hilmi Volkan Acar, Havva Yagci School of Physical and Mathematical Sciences School of Electrical and Electronic Engineering School of Materials Science and Engineering LUMINOUS! Centre of Excellence for Semiconductor Lighting & Displays The Photonics Institute Science::Chemistry Nanoplatelet Cancer Cells Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loaded NPLs emerged as a new class of theranostic nanoparticles for image-guided enhanced photodynamic therapy of both androgen-dependent and -independent human prostate cancer cells. KO thanks Koc University Seed Fund for the financial support. HVD also acknowledges the support from TU¨BA. 2023-11-24T02:17:18Z 2023-11-24T02:17:18Z 2023 Journal Article Onbasli, K., Demirci, G., Isik, F., Durmusoglu, E. G., Demir, H. V. & Acar, H. Y. (2023). Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells. Chemical Communications, 59(70), 10512-10515. https://dx.doi.org/10.1039/D3CC02929H 1359-7345 https://hdl.handle.net/10356/172114 10.1039/D3CC02929H 70 59 10512 10515 en Chemical Communications © 2023 The Royal Society of Chemistry. All rights reserved.
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Chemistry
Nanoplatelet
Cancer Cells
spellingShingle Science::Chemistry
Nanoplatelet
Cancer Cells
Onbasli, Kubra
Demirci, Gozde
Isik, Furkan
Durmusoglu, Emek Goksu
Demir, Hilmi Volkan
Acar, Havva Yagci
Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
description Fluorescent, CdSe/CdS core/crown heterostructured nanoplatelets (NPLs) were transferred to the water via a simple, single-step ligand exchange using 2-mercaptopropionic acid in a simple extraction process. These stable, aqueous NPLs were loaded with a modal drug, 5-aminolevulinic acid (ALA). ALA-loaded NPLs emerged as a new class of theranostic nanoparticles for image-guided enhanced photodynamic therapy of both androgen-dependent and -independent human prostate cancer cells.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Onbasli, Kubra
Demirci, Gozde
Isik, Furkan
Durmusoglu, Emek Goksu
Demir, Hilmi Volkan
Acar, Havva Yagci
format Article
author Onbasli, Kubra
Demirci, Gozde
Isik, Furkan
Durmusoglu, Emek Goksu
Demir, Hilmi Volkan
Acar, Havva Yagci
author_sort Onbasli, Kubra
title Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
title_short Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
title_full Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
title_fullStr Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
title_full_unstemmed Aqueous colloidal nanoplatelets for imaging and improved ALA-based photodynamic therapy of prostate cancer cells
title_sort aqueous colloidal nanoplatelets for imaging and improved ala-based photodynamic therapy of prostate cancer cells
publishDate 2023
url https://hdl.handle.net/10356/172114
_version_ 1783955600015622144

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