Modelling genetic polycystic kidney disease using human pluripotent stem cell-derived kidney organoids

• Main Author: Liu, Meng
• Other Authors: Xia Yun
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2023
• Subjects: Science::Biological sciences::Genetics; Science::Medicine::Tissue engineering; Science::Biological sciences::Molecular biology
• Online Access: https://hdl.handle.net/10356/172816
• Institution: Nanyang Technological University

Polycystic kidney disease (PKD) is an inherited disorder characterized by progressive expansion of fluid-filled cysts in the kidney. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) represent the most common forms of PKD. Treatment option...