Investigating neurodevelopmental defects in MELAS syndrome using neural organoids derived from induced pluripotent stem cells
Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome is characterised by many neurological symptoms such as dementia and epilepsy. One of the most prevalent mutation in MELAS is the m.A3243G transition within the MT-TL1 gene, that encodes for mitochondrial tRNAL...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/76217 |
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| Institution: | Nanyang Technological University |
| Language: | English |