Modelling genetic polycystic kidney disease using human pluripotent stem cell-derived kidney organoids

• 主要作者: Liu, Meng
• 其他作者: Xia Yun
• 格式: Thesis-Doctor of Philosophy
• 語言: English
• 出版: Nanyang Technological University 2023
• 主題: Science::Biological sciences::Genetics; Science::Medicine::Tissue engineering; Science::Biological sciences::Molecular biology
• 在線閱讀: https://hdl.handle.net/10356/172816

Polycystic kidney disease (PKD) is an inherited disorder characterized by progressive expansion of fluid-filled cysts in the kidney. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) represent the most common forms of PKD. Treatment option...