Deep transcriptome profiling reveals limited conservation of A-to-I RNA editing in Xenopus

• Main Authors: Nguyen, Tram Anh, Heng, Joel Jia Wei, Ng, Yan Ting, Sun, Rui, Fisher, Shira, Oguz, Gokce, Kaewsapsak, Pornchai, Xue, Shifeng, Reversade, Bruno, Ramasamy, Adaikalavan, Eisenberg, Eli, Tan, Meng How
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Science::Biological sciences; RNA Editing; Xenopus
• Online Access: https://hdl.handle.net/10356/173050
• Institution: Nanyang Technological University

Background: Xenopus has served as a valuable model system for biomedical research over the past decades. Notably, ADAR was first detected in frog oocytes and embryos as an activity that unwinds RNA duplexes. However, the scope of A-to-I RNA editing by the ADAR enzymes in Xenopus remains underexplore...